The hill is known for its high number of automobile accidents. It is a steep descent into the valley of the Ohio River between Kyles Lane and the Brent Spence Bridge leading into Downtown Cincinnati. As a result, the northbound descent into Cincinnati, known as Cut-in-the-Hill, was nicknamed ' Death Hill'. The stretch through Covington originally included hills and curves steeper than those recommended for Interstate Highway standards.

It then passes through Covington and crosses the Ohio River via the lower level of the Brent Spence Bridge into Ohio. On the north side of Florence, I-75 intersects with the only auxiliary route it has in the state, I-275, a beltway bypass of the greater Cincinnati area. The two routes remain concurrent through to Downtown Cincinnati. Just south of Florence, the route enters the Cincinnati metropolitan area and becomes concurrent with I-71. It meets and then becomes briefly concurrent with I-64 along the north and east sides of Lexington, before leaving the Lexington area northerly and bypassing Georgetown en route to Cincinnati, Ohio. The highway continues north through Richmond en route to Lexington. The freeway enters Kentucky south of Williamsburg in the Cumberland Plateau, bypassing Corbin and London before descending into the Bluegrass region near Berea through the Pottsville Escarpment. I-75 runs roughly parallel to US 25 for its entire length in Kentucky. I-75 (and I-71) heading northbound into Cincinnati from Covington Route 25 (US 25) corridor for the entire length of Kentucky. I-75 enters the Cumberland Plateau region from Tennessee, then descends into the Bluegrass region through the Pottsville Escarpment before crossing the Ohio River into Ohio. Interstate 75 ( I-75) runs from near Williamsburg to Covington by way of Lexington in the US state of Kentucky.

Whitley, Laurel, Rockcastle, Madison, Fayette, Scott, Grant, Boone, Kenton

I75 traffic kentucky